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Vitamin C and your health | healthdirect Cancer Epidemiol.Biomarkers Prev. Cochrane Database Syst Rev. Pedersen, B. K., Helge, J. W., Richter, E. A., Rohde, T., and Kiens, B. However, this does not appear to be the case. Lancet 11-27-1993;342(8883):1325-1328. View abstract. geriatric network. Metabolism of ascorbic acid (vitamin C) in subjects infected with common cold viruses. Ferlin MLS, Chuan LS, Jorge SM, and Vannucchi H. Early anemia of prematurity. Arterioscler.Thromb.Vasc.Biol. View abstract. Although avoiding certain foods is important for a colonoscopy procedure, some people dont adhere to these instructions. View abstract. Dement.Geriatr.Cogn Disord. Lung function and blood levels of copper, selenium, vitamin C and vitamin E in the general population. Arch Neurol 2003;60:203-8.. View abstract. The authors concluded that taking high doses of vitamins A, E, D, C, and folic acid did not always help prevent disease, and in some situations could be harmful. View abstract. Clin.Pediatr. Wilson, C. W., Greene, M., and Loh, H. S. The metabolism of supplementary vitamin C during the common cold. Ascorbate is depleted by smoking and replaced by moderate supplementation: a study in male smokers and nonsmokers with matched dietary antioxidant intakes. Papoulidis, P., Ananiadou, O., Chalvatzoulis, E., Ampatzidou, F., Koutsogiannidis, C., Karaiskos, T., Madesis, A., and Drossos, G. The role of ascorbic acid in the prevention of atrial fibrillation after elective on-pump myocardial revascularization surgery: a single-center experience--a pilot study. 1981;43(1):174-179. View abstract. 2007;177(2):639-643. J Cosmet Dermatol 2021. The Adventist Health Study. Eur Heart J 1994;15:168. Am.J Epidemiol. What are the side effects of taking vitamins? Majidi N, Rabbani F, Gholami S, et al. Diet and asthma in Dutch school children (ISAAC-2). Lancet 7-20-1991;338(8760):131-137. Common prostate problems 6 signs of prostate problems and [], Article Contents What is an enlarged prostate? Wang L, Sesso HD, Glynn RJ, et al. The Age-Related Eye Disease Study system for classifying age-related macular degeneration from stereoscopic color fundus photographs: the Age-Related Eye Disease Study Report Number 6. A clinical trial of antioxidant vitamins to prevent colorectal adenoma. View abstract. Some people complain of a bitter taste in the mouth. Am.J Clin.Nutr 1993;57(2):170-174. by a factor of 3.5. View abstract. View abstract. Far more delicious, safer, and much more interesting! View abstract. Hung KC, Lin YT, Chen KH, et al. Ginger, lime, and other aromatics add a lot of . 2008;(2):CD007176. J Int Med Res 1992;20(3):227-233. This is because colonoscopies require using a colonoscope which is inserted inside the rectum and colon. If your body has enough vitamins on board, if you take extra vitamins, you will simply excrete them in your urine and feces. In the UK, calcium and vitamin D supplementation is recommended for perimenopausal or postmenopausal women at risk of osteoporosis, as it has been shown to improve bone mineral density and prevent fracture. Baird IM, Hughes RE, Wilson HK, et al. N Engl J Med 2004;350:2673-81. Which Vitamins are Recommended? Association about dietary vitamin C intake on the risk of ovarian cancer: A meta-analysis. I also underwent a computed tomography (CT) scan, and nothing major was found, but I am worried as the doctor wants to meet me to discuss the findings of the CT scan in detail. View abstract. View abstract. View abstract. Bjelakovic G, Nikolova D, Simonetti RG, Gluud C. Antioxidant supplements for prevention of gastrointestinal cancers: a systematic review and meta-analysis. Charoenlarp, P., Pholpothi, T., Chatpunyaporn, P., and Schelp, F. P. The effect of riboflavin on the hematologic changes in iron supplementation of schoolchildren. Grievink, L., de Waart, F. G., Schouten, E. G., and Kok, F. J. Serum carotenoids, alpha-tocopherol, and lung function among Dutch elderly. Johnston CS, Bowling DL. Eur.J Clin.Nutr 1992;46(11):803-808. Dietary intakes of vitamin E, vitamin C, and -carotene and risk of Alzheimer's disease: a meta-analysis. Am J Clin Nutr 1975;28:550-4. View abstract. Allsup, S. J., Shenkin, A., Gosney, M. A., Taylor, S., Taylor, W., Hammond, M., and Zambon, M. C. Can a short period of micronutrient supplementation in older institutionalized people improve response to influenza vaccine? Pressman, E. K., Cavanaugh, J. L., Mingione, M., Norkus, E. P., and Woods, J. R. Effects of maternal antioxidant supplementation on maternal and fetal antioxidant levels: a randomized, double-blind study. Read our Editorial Process to know how we create content for health articles and queries. Human HL-60 myeloid leukemia cells transport dehydroascorbic acid via the glucose transporters and accumulate reduced ascorbic acid. View abstract. J Nutr 1996;126(1):121-128. chemotherapy in patients with advanced cancer: a phase I-II clinical trial. [Low concentration of alpha-tocopherol in erythrocytes of atopic dermatitis patients]. J Am Coll Nutr. View abstract. When Is the Best Time to Take Vitamins? - Verywell Fit Eur.Respir.J 2001;17(3):436-443. Zipursky A, Brown EJ, Watts J, et al. View abstract. 5-15-2000;151(10):975-981. Hartgrink, H. H., Wille, J., Konig, P., Hermans, J., and Breslau, P. J. Forli, L., Pedersen, J. I., Bjortuft, O., Blomhoff, R., Kofstad, J., and Boe, J. Vitamins A and E in serum in relation to weight and lung function in patients with advanced pulmonary disease. View abstract. Clin.Exp.Allergy 2007;37(1):54-61. Sunkara V, Pelkowski TD, Dreyfus D, Satoskar A. Terry, P., Lagergren, J., Ye, W., Nyren, O., and Wolk, A. Antioxidants and cancers of the esophagus and gastric cardia. View abstract. View abstract. van den Broek, N. R., White, S. A., Flowers, C., Cook, J. D., Letsky, E. A., Tanumihardjo, S. A., Mhango, C., Molyneux, M., and Neilson, J. P. Randomised trial of vitamin A supplementation in pregnant women in rural Malawi found to be anaemic on screening by HemoCue. Lancet 11-7-1992;340(8828):1124-1127. 2002;50(1-2):10-13. Taking 1-3 grams of vitamin C by mouth might shorten the course of a cold by 1 to 1.5 days. What is the best time of the day to have Vitamin C? - The Times of India View abstract. View abstract. Circulation 2003;108:1059-63.. View abstract. View abstract. View abstract. Ushiyama, Y., Matsumoto, K., Shinohara, M., Wakiguchi, H., Sakai, K., Komatsu, T., and Yamamoto, S. Nutrition during pregnancy may be associated with allergic diseases in infants. Taylor, T. V., Rimmer, S., Day, B., Butcher, J., and Dymock, I. W. Ascorbic acid supplementation in the treatment of pressure-sores. Long-term ascorbic acid administration reverses endothelial vasomotor dysfunction in patients with coronary artery disease. View abstract. Dermatol Ther 2022; 35(5):e15376. 2009;29(2):150-7. doi:10.1016/j.asj.2009.01.002, Bajwa SJ, Panda A. Nightingale, A. K., Blackman, D. J., Field, R., Glover, N. J., Pegge, N., Mumford, C., Schmitt, M., Ellis, G. R., Morris-Thurgood, J. View abstract. Gokce, N., Keaney, J. F., Jr., Frei, B., Holbrook, M., Olesiak, M., Zachariah, B. J., Leeuwenburgh, C., Heinecke, J. W., and Vita, J. Barel AO, Delune M, Clarys P, and Gabard B. Int J Vitam.Nutr Res. Association between vitamin C intake and the risk of pancreatic cancer: a meta-analysis of observational studies. Large amounts of vitamin C might decrease how much fluphenazine is in the body. For example, a single-dose preparation might result in more forceful bowel movements that begin faster than a split-dose option. 2012;59(6):538-43. Cochrane Database Syst Rev. Fractures. He is able to simplify complex concepts for general audiences and add a scientific element to the related topics. Bodner, C., Godden, D., Brown, K., Little, J., Ross, S., and Seaton, A. Antioxidant intake and adult-onset wheeze: a case-control study. 7-1-1998;148(1):38-44. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, 6 Minutes of Exercise May Protect Brain From Alzheimer's, 'Disturbing' Rate of Adverse Events During Hospital Stays. View abstract. Li, W., Zhu, Y., Yan, X., Zhang, Q., Li, X., Ni, Z., Shen, Z., Yao, H., and Zhu, J. View abstract. Sadat U, Usman A, Gillard JH, Boyle JR. Arch Intern Med 2004;164:2335-42. Associations between antioxidant and zinc intake and the 5-year incidence of early age-related maculopathy in the Beaver Dam Eye Study. It seems that there are risks associated with taking, Many people believe high dose vitamin C can prevent upper respiratory infections. 1997;66(1):177-183. But taking vitamin C does not appear to prevent. View abstract. Grievink, L., Smit, H. A., Ocke, M. C., Van, 't, V, and Kromhout, D. Dietary intake of antioxidant (pro)-vitamins, respiratory symptoms and pulmonary function: the MORGEN study. Step 3: Drink the water from the bottle, making sure to keep your lips firmly sealed around the bottle. Ann Allergy 1990;65:311-4. Am.J.Clin.Nutr. View abstract. View abstract. 2015;66(4):721-4. During this time, patients stick to a clear liquid diet for all meals of the day (breakfast, lunch, and dinner). Knekt P, Reunanen A, Jarvinen R, et al. Foot Ankle Surg 2019;25(4):542-5. doi: 10.1016/j.fas.2018.05.001. Trials. 2005;24(6):979-987. 9-20-1990;323(12):789-795. 6-3-1950;143(5):421-424. The vitamin C controversy. 8-13-2007;167(15):1610-1618. Nutr Cancer 1993;19(3):327-335. 11-24-1956;162(13):1224-1226. Effect of vitamin C &E supplementation of pregnant women at risk of preeclampsia plus low nutritional status: the WHO trial. J Intern Med 2000;248:377-86. Reaven, P. D., Herold, D. A., Barnett, J., and Edelman, S. Effects of Vitamin E on susceptibility of low-density lipoprotein and low-density lipoprotein subfractions to oxidation and on protein glycation in NIDDM. View abstract. Wilson, C. W., Loh, H. S., and Foster, F. G. Common cold symptomatology and vitamin C. Eur.J Clin.Pharmacol. Age-Related Eye Disease Study Research Group. View abstract. Carotenoids, vitamins C and E, and mortality in an elderly population. J Clin.Epidemiol. You can learn more about how we ensure our content is accurate and current by reading our. Moor de, Burgos A., Wartanowicz, M., and Ziemlanski, S. Blood vitamin and lipid levels in overweight and obese women. Spinnato, J. Eur.Respir.J 2007;29(6):1161-1168. Am J Med Sci 2021. Bromelain. Kendall, A. C., Jones, E. E., Wilson, C. I., Shinton, N. K., and Elwood, P. C. Folic acid in low birthweight infants. 2001;250(2):167-9. doi:10.1046/j.1365-2796.2001.00851.x, Rowe DJ, Baker AC. 2020;92(3):554-564. J Natl Cancer Inst 1993;85:1483-92. Daily sunscreen applications and beta-carotene supplementation in prevention of basal-cell and squamous-cell carcinomas of the skin: a randomized controlled trial. Malo, J. L., Cartier, A., Pineau, L., L'Archeveque, J., Ghezzo, H., and Martin, R. R. Lack of acute effects of ascorbic acid on spirometry and airway responsiveness to histamine in subjects with asthma. Stick to their instructions and avoid eating anything unless a doctor says its okay. View abstract. The effect of folic acid and iron in the prevention of nutritional anaemias in pregnancy in Nigeria. Greenberg ER, Baron JA, Tosteson TD, et al. View abstract. 5-15-2004;159(10):959-967. Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the selenium and vitamin E cancer prevention trial (SELECT). Pediatrics 1984;74:103-11.. View abstract. Int J Cancer. Diabetes Care 1995;18(6):807-816. Sperduto RD, Hu TS, Milton RC, et al. Effect of ascorbic acid on microcirculation in patients with Type II diabetes: a randomized placebo-controlled cross-over study. Premenopausal breast cancer risk and intake of vegetables, fruits, and related nutrients. Ear Nose Throat J 2000;79:778-82.. View abstract. View abstract. 2003;22(1):18-35. Otolaryngol Head Neck Surg. It's also important to take vitamin B6 during the day. Invest Ophthalmol Vis Sci 1996;37:1225-35. View abstract. Therapeutic Research Faculty 2018. View abstract. Vitamin C deficiency is associated with high risk of myocardial infarction in eastern Finnish men. 2006;21(1):234-235. View abstract. Groenbaek, K., Friis, H., Hansen, M., Ring-Larsen, H., and Krarup, H. B. View abstract. Juraschek, S. P., Guallar, E., Appel, L. J., and Miller, E. R., III. Keya TA, Leela A, Fernandez K, Habib N, Rashid M. Effect of Vitamin C Supplements on Respiratory Tract Infections: A Systematic Review and Meta-Analysis. Int J Vitam.Nutr Res. The Iowa Women's Health Study. Grodstein, F., Chen, J., and Willett, W. C. High-dose antioxidant supplements and cognitive function in community-dwelling elderly women. 2006;47(4):644-654. Dietary fiber, vitamins A, C, and E, and risk of breast cancer: a cohort study. Ghosh, S. K., Ekpo, E. B., Shah, I. U., Girling, A. J., Jenkins, C., and Sinclair, A. J. de Valk, H. W., Hardus, P. L., van Rijn, H. J., and Erkelens, D. W. Plasma magnesium concentration and progression of retinopathy. Cochrane Database Syst Rev 2000;2:CD000530.. View abstract. View abstract. Am.J Respir.Crit Care Med 1996;154(5):1401-1404. View abstract. Clinically insignificant effect of supplemental vitamin C on serum urate in patients with gout: a pilot randomized controlled trial. Science 2001;292:2083-4. Simon JA, Hudes ES. A randomized double-blind comparison. View abstract. Am.J Epidemiol. 2012;13(5):542-5. View abstract. Ascorbic acid and intestinal metaplasia in the stomach: a prospective, randomized study. A meta-analysis. View abstract. Int J Pediatr.Otorhinolaryngol. Clin Infect.Dis 9-1-2002;35(5):618-624. Shahrekord Univ Med Sci J 2007;1:50-54. Doctors usually advise patients to stop eating solid foods 24 hours before the procedure. Cook JD, Reddy MB. Negri E, Franceschi S, Bosetti C, et al. View abstract. Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes. 1999;14(1):21-27. Nja, F., Nystad, W., Lodrup Carlsen, K. C., Hetlevik, O., and Carlsen, K. H. Effects of early intake of fruit or vegetables in relation to later asthma and allergic sensitization in school-age children. McKeever, T. M., Lewis, S. A., Smit, H. A., Burney, P., Cassano, P. A., and Britton, J. View abstract. Acta Med Scand. It seems that there are risks associated with taking vitamin E at high doses. If you think about it is this way, you will remember to disclose all the vitamins, supplements, and medications you take regularly. J Am Diet Assoc 1980;76:581-4.. View abstract. N Engl J Med 1997;336:1216-22. Take vitamin C two hours before or four hours after antacids. Add some fruit juice, Crystal Light, or ice to the laxative to help make it taste better. Other foods include black tea or coffee, popsicles, and Jell-O. View abstract. Am.J Epidemiol. In fact, diarrhea tends to be forceful in this case, which is why you may have bloating or cramps. Mooney, L. A., Madsen, A. M., Tang, D., Orjuela, M. A., Tsai, W. Y., Garduno, E. R., and Perera, F. P. Antioxidant vitamin supplementation reduces benzo(a)pyrene-DNA adducts and potential cancer risk in female smokers. If you are thinking about vitamins, why not concentrate of improving your diet instead? View abstract. The effect of antioxidant supplementation on hepatitis C viral load, transaminases and oxidative status: a randomized trial among chronic hepatitis C virus-infected patients. Robson, P. J., Bouic, P. J., and Myburgh, K. H. Antioxidant supplementation enhances neutrophil oxidative burst in trained runners following prolonged exercise. View abstract. View abstract. BMJ 10-13-2007;335(7623):755. Eye (Lond) 2008;22(6):751-760. 2002;7(5):310-316. View abstract. No food or liquid three hours before your scheduled procedure. Osifo, B. O. J.Natl.Cancer Inst. N.Engl.J Med. Some hospitals may even require or request it. Obstet Gynecol. For females 19 years and older, the RDA is 75 mg daily. Ask your health query to a doctor online? J Am Coll Cardiol 2000;35:1616-21.. View abstract. Aust.N.Z.J Ophthalmol. Dietary adjustments start three to five days before the procedure. Cancer Epidemiol.Biomarkers Prev. View abstract. Nutr Res 1991;11:405-412. J Cardiovasc Risk 1996;3:513-521.. View abstract. 2005;39(12):2073-2080. View abstract. View abstract. Oral administration of RAC-alpha-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: a placebo-controlled, pilot trial. OTHER NAMES(S): Acide Ascorbique, Acide Cvitamique, Acide Iso-Asc, OTHER NAME(S): Acide Ascorbique, Acide Cvitamique, Acide Iso-Asc. View abstract. Emadi N, Nemati MH, Ghorbani M, Allahyari E. The effect of high-dose vitamin C on biochemical markers of myocardial injury in coronary artery bypass surgery. Effects of ramipril and vitamin E on atherosclerosis: the study to evaluate carotid ultrasound changes in patients treated with ramipril and vitamin E (SECURE). What Vitamins and Supplements Should Not Be Taken Together? - MedicineNet J Nutr 1979;109:819-26.. View abstract. Cutis 2001;68(2):135-142. Eur.Urol. A., Cole, B. F., Mott, L., Haile, R., Grau, M., Church, T. R., Beck, G. J., and Greenberg, E. R. Neoplastic and antineoplastic effects of beta-carotene on colorectal adenoma recurrence: results of a randomized trial. View abstract. Eur.J Epidemiol. Shu, X. O., Zheng, W., Potischman, N., Brinton, L. A., Hatch, M. C., Gao, Y. T., and Fraumeni, J. F., Jr. A population-based case-control study of dietary factors and endometrial cancer in Shanghai, People's Republic of China. 2004;44(5):594-603. Singh, A., Papanicolaou, D. A., Lawrence, L. L., Howell, E. A., Chrousos, G. P., and Deuster, P. A. Neuroendocrine responses to running in women after zinc and vitamin E supplementation. A prospective study of diet and adult-onset asthma. Machtey, I. and Ouaknine, L. Tocopherol in Osteoarthritis: a controlled pilot study. Is Centrum Silver made in the United States? View abstract. Circulation 2001;104:2182-7.. View abstract. Buzina, R., Grgic, Z., Jusic, M., Sapunar, J., Milanovic, N., and Brubacher, G. Nutritional status and physical working capacity. Mathew, M. C., Ervin, A. M., Tao, J., and Davis, R. M. Antioxidant vitamin supplementation for preventing and slowing the progression of age-related cataract. [RETRACTED]. View abstract. 36th Am Soc Clin Oncol Ann Mtg Prog Proceedings/Abstracts: Abstract 2367. Lee NA, Reasner CA. In many cases, the patient needs to take a laxative the night before the procedure. Circulation 2001;103:919-25. Five days before the procedure, patients need to stop eating high-fiber foods and consume a low-fiber diet instead. View abstract. Mayne ST, Risch HA, Dubrow R, et al. View abstract. Li T, Zeng J, Li DH, et al. 2009;13(43):1-627. View abstract. Do nutritional supplements lower the risk of stroke or hypertension? 12-18-1954;156(16):1501. View abstract. 2014;52(9):984. (Lond) 1942;42(1):1-19. However, a large, 2006, randomized trial of 36,282 postmenopausal women who took calcium and vitamin D supplements for 7 years, did not show any reduction in colonic cancer incidence. Rasoli, S., Kourliouros, A., Harling, L., and Athanasiou, T. Does prophylactic therapy with antioxidant vitamins have an effect on atrial fibrillation following cardiac surgery? View abstract. View abstract. View abstract. View abstract. View abstract. Am.J.Clin.Nutr. Pietinen P, Rimm EB, Korhonen P, et al. Oral vitamin E supplementation for the prevention of anemia in premature infants: a controlled trial. Aberdeen WHEASE Study Group. Jacobson, J. S., Begg, M. D., Wang, L. W., Wang, Q., Agarwal, M., Norkus, E., Singh, V. N., Young, T. L., Yang, D., and Santella, R. M. Effects of a 6-month vitamin intervention on DNA damage in heavy smokers. Int J Vitam Nutr Res 1995;65(2):117-121. For example, it's better to take vitamin B12 in the morning for this reason. Br J Nutr 1990;64(2):351-358. View abstract. Vitamin C might decrease how the body removes aspirin and could potentially increase the amount of aspirin in the body. Vitamin C-induced decomposition of lipid hydroperoxides to endogenous genotoxins. Liljefors, I. Mente, A., de, Koning L., Shannon, H. S., and Anand, S. S. A systematic review of the evidence supporting a causal link between dietary factors and coronary heart disease. A., Wolen, R. L., Griffith, R. S., and Rose, R. J. of the University Clinic of Wurzburg, Wurzburg, Germany 1986; Li, G., Li, L., Yu, C., and Chen, L. Effect of vitamins C and E supplementation on Helicobacter pylori eradication: a meta-analysis. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Chen, H., Tucker, K. L., Graubard, B. I., Heineman, E. F., Markin, R. S., Potischman, N. A., Russell, R. M., Weisenburger, D. D., and Ward, M. H. Nutrient intakes and adenocarcinoma of the esophagus and distal stomach. 2009;41(9):644-647. Common cold. Fleming, A. F., Hendrickse, J. P., and Allan, N. C. The prevention of megaloblastic anaemia in pregnancy in Nigeria. Skelin M, Lucijanic T, Amidzic Klaric D, et al. View abstract. Citrus fruits, berries, tomatoes, potatoes, and green . Taking vitamin C along with estrogens might increase the effects and side effects of estrogens. Am J Epidemiol 7-15-1996;144(2):165-174. View abstract. navigator.sendBeacon('https://www.google-analytics.com/collect', payload); Results: We reviewed colonoscopy preparation instructions from 317 endoscopy units, of which 138 (43.5%) recommended continuing aspirin, 103 (32.5%) recommended stopping aspirin, and 76 (24%) requested patients to contact a physician. As usual, individual experiences can vary. Filho RL, Lima MB, Kneipp R, Cunha LC, and Ogliari M. Alteracoes dos niveis sericos de cholesterol, em pacientes sob o uso de acido ascorbico. View abstract. Effect of ascorbic acid intake on nonheme-iron absorption from a complete diet. View abstract. Mov Disord. Buzina, R., Jusic, M., Milanovic, N., Sapunar, J., and Brubacher, G. The effects of riboflavin administration on iron metabolism parameters in a school-going population. View abstract. Anderson, T. W., Reid, D. B., and Beaton, G. H. Vitamin C and the common cold. Thorax 2001;56(1):48-52. Dr. Hotez says . In addition to the potential problems with surgery noted below, many herbal supplements can interact with commonly prescribed medications. Vitamin C intake and mortality among a sample of the United States population. Lancet 4-8-2000;355(9211):1271-1272. Colonoscopy - Getting ready - NHS Singh, N., Graves, J., Taylor, P. D., Macallister, R. J., and Singer, D. R. Effects of a 'healthy' diet and of acute and long-term vitamin C on vascular function in healthy older subjects. Taking vitamin C by mouth after surgery or injury seems to prevent complex regional pain syndrome from developing. 2021;13(1):24. Health Technol.Assess. View abstract. Milner, J. D., Stein, D. M., McCarter, R., and Moon, R. Y. 2009;54(6):1089-1097. J Formos.Med Assoc 1992;91(3):270-275. As a doctor, I am often asked: Read onand to ensure your health and the health of others, don't miss these Signs Your Illness is Actually Coronavirus in Disguise. We avoid using tertiary references. Bloem, M. W., Wedel, M., van Agtmaal, E. J., Speek, A. J., Saowakontha, S., and Schreurs, W. H. Vitamin A intervention: short-term effects of a single, oral, massive dose on iron metabolism. Jackson, R. T. and Latham, M. C. Anemia of pregnancy in Liberia, West Africa: a therapeutic trial. They proposed that vitamins should be only issued under the control of a trained pharmacist. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E and beta carotene for age-related cataract and vision loss: AREDS report no. View abstract. B., Belle, S. H., Stoehr, G. P., and Ganguli, M. Use of antioxidant supplements and its association with cognitive function in a rural elderly cohort: the MoVIES Project. J Natl.Cancer Inst. View abstract. View abstract. Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study. If you take vitamin C supplements, do not take too much as this could be harmful. The Best Time to Take Vitamins - Cleveland Clinic Arch Intern Med 1992;152(7):1416-1424. Davies JE, Hughes RE, Jones E, et al. Pathak, A. K., Bhutani, M., Guleria, R., Bal, S., Mohan, A., Mohanti, B. K., Sharma, A., Pathak, R., Bhardwaj, N. K., Prasad, K. N., and Kochupillai, V. Chemotherapy alone vs. chemotherapy plus high dose multiple antioxidants in patients with advanced non small cell lung cancer. 2011;26(1):68-78. J Natl Cancer Inst 1998;90:440-6. Cancer Epidemiol Biomarkers Prev 1994;3:161-6. 1984;54(1):55-60. Vitamin C is also a powerful antioxidant that supports the immune response. View abstract. View abstract. Int J Cancer 11-4-1996;68(3):300-304. Effects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trial. Cochrane.Database.Syst.Rev. Nutrition intervention trials in Linxian, China: multiple vitamin/mineral supplementation, cancer incidence, and disease-specific mortality among adults with esophageal dysplasia.